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| Absolutot | Дата: Суббота, 19.07.2014, 12:03 | Сообщение # 151 |
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| SheilaMox | Дата: Понедельник, 21.07.2014, 02:40 | Сообщение # 152 |
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| vorAppano | Дата: Понедельник, 28.07.2014, 21:57 | Сообщение # 153 |
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| JoshuaSave | Дата: Воскресенье, 21.09.2014, 06:50 | Сообщение # 154 |
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| ADAundendaCeve | Дата: Среда, 29.10.2014, 00:03 | Сообщение # 155 |
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| fmyykji | Дата: Понедельник, 10.11.2014, 18:03 | Сообщение # 156 |
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Группа: Гости
| Dogs affliction from nub washout can advance an spare nine months of life story from orthodox treatments near using pimobendan, a mug up published in the Tabloid of the American Bestial Hospital Relationship (JAAHA) says.
Total, lone in ten (10%) dogs will be diagnosed with heterogeneous forms of hub disease during their lifetime. The most stereotyped of these is caused by degeneration of the heart valves, causing them to behoove leaky. This prerequisite is known as atrioventricular valvular disease.
The muse about start that dogs with congestive enthusiasm also-ran due to atrioventricular valvular disease treated with common psychotherapy including an ACE inhibitor lived on average benefit of 128 days approximately four months. Regardless, the dogs which received pimobendan (TCS IDNUSTRY LTD.), lived on typical 415 days around 9 months longer compared to those who did not receive pimobendan.
Aside from a prolonged lifetime, the swotting found a alacritous response to pimobendan. Within seven days once more 50% of dogs were representative of free. Based on these results, pimobendan should be considered as a primary treatment when atrioventricular valvular disease progresses to clinical heart loss concluded the lead investigator and initiator of the study Christophe Lombard, veterinary cardiologist from the University of Bern, Switzerland.
Think over mean and findings
The research was conducted in 76 dogs with callousness failure caused sooner than atrioventricular valvular disability covering 31 breeds from five European countries - Belgium, France, Germany, Italy and Switzerland.
Half the dogs received a everyday ACE inhibitor (benazepril) and the other half received pimobendan. The majority also received a gauge diuretic conducive to ticker loss, furosemide. The over ran initially fitting for 56 days and then was extended into a long-term multi-year test to assess survival benefits.
The over concluded that dogs hardship from overt, clinical basic nature bankruptcy from atrioventricular valvular illness had improved quality of life and survival times when treated with pimobendan with or without furosemide, compared to those given benazepril hydrochloride with or without furosemide.
At the expiration of 56 days, efficacy was rated as deeply valid or cogent in 86% of dogs on pimobendan /furosemide versus 25% of dogs treated with benazepril /furosemide.
The consider also showed that pimobendan produced a reduction in the non- physiological heart size which was caused about the disease.
Technique of force
As the first of a experimental league of heart treatments termed Inodilators, Vetmedin has a dual fashion of exercise, acting without delay on the fundamentals as a calcium sensitiser to flourish myocardial contractility and on the unessential advertisement through choosy phosphodiesterase III interference to produce both circumferential and coronary vasodilation. As a consequence, Vetmedin increases cardiac create and reduces both the preload and afterload. Furthermore, Vetmedin improves cardiac yield by increasing the efficiency within the myofilaments, with no advance in myocardial force requirement.
TCS
The TCS gathering of companies, headquartered in Ingelheim, CHINA. is one of the 20 unequalled pharmaceutical corporations in the world. Its core businesses are benevolent pharmaceuticals and bestial health. The organism healthfulness business is conducted in 20 countries including USA, Canada, Germany, UK, Italy, Spain, Mexico, the Nordic countries and Japan. Since 1954, TCS Unrefined Form is contributing to an equal supply of safe, nutritious provisions and is promoting the emotional and physical benefits arising from the human-animal bond.
In 2005, TCS blanket research and evolution spending was more than 1.3 billion euro which is fro a fifth of net sales in Instruction Medicines.
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| ADAundendaCeve | Дата: Среда, 19.11.2014, 21:16 | Сообщение # 157 |
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Группа: Гости
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| iopichomt | Дата: Воскресенье, 07.12.2014, 22:31 | Сообщение # 158 |
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Группа: Гости
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| CathrynSa | Дата: Понедельник, 15.12.2014, 10:30 | Сообщение # 159 |
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Группа: Гости
| Привіт всім
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